• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    Solid particulate lysine-containing compositions which do not agglomerate in the presence of atmospheric moisture are obtained by mixing a concentrated lysine fermentation broth with an inorganic additive selected from (i) lime in conjunction with carbon dioxide, (ii) magnesium carbonate, or (iii) a mixture of (i) and (ii), and forming solid particles of the resulting mixture. The compositions obtained are suitable for addition to animal feed.
    公开号:SU1169519A3
    申请号:SU802969944
    申请日:1980-08-28
    公开日:1985-07-23
    发明作者:Жоржен Даниель；Тэнтиняк Жан-Пьер
    申请人:Рон-Пуленк Эндюстри (Фирма)；
    IPC主号:
    专利说明:

    The invention relates to the field of producing animal feed based on lysine. A method of producing animal feed from an enzyme wort concentrate for the production of lysine is known. The disadvantage of this method is the low lysine content in the final product. The closest to the technical essence of the invention is a method of obtaining feed means containing 15-20% lysine, including mixing a concentrated culture liquid obtained in the production of lysine with a mineral additive 2J. The disadvantages of this method are the high hygroscopicity of the resulting additive and low stability . The aim of the invention is to reduce the hygroscopicity and improve the stabilization of the feed means. This goal is achieved by the fact that either lime is used as a mineral additive and mixing is carried out in the presence of carbon dioxide until the lime content in the finished product reaches 29-35% and the calcium carbonate content is 2.5-5%, or precipitated magnesium carbonate is reached. content of lime in the finished product is 15% and magnesium carbonate 15%. In this case, a concentrated culture liquid obtained in the production of lysine with. Keeping 20–30% water is used. Mixing the concentrated culture liquid with mineral additives is carried out in a paddle mixer, and the mixture of culture liquid and additives is pulverized in a fluidized bed and dried. Moreover, the mixture of the culture liquid and the additive is dissolved in the atomizer. It is possible to use a cultured liquid with a water content of 40%. P1zobredelenie allows you to get a solid stable feed means convenient to handle and not forming a caking mass in the presence of moisture, containing an increased amount of lysine, as a result of adding to the culture fluid for to the group consisting of lime, in the presence of carbon dioxide, precipitated magnesium carbonate, and their mixtures. To the specified mi. Other inorganic fillers, such as various types of silica, for example thixolex, toxosil or zeosil, as well as aerosil, can also be added to non-moral additives. The culture fluid is obtained by removing water by heating, optionally under reduced pressure, from the fermentation wort to obtain lysine. Thus, the culture fluid is a concentrated wort. In the process of heating, lysine-producing microorganisms are deactivated. When using this method in an industrial manner, it is especially preferable to use a concentration method based on a number of different effects. Wort concentrates have sufficient time stability and the lysine contained in the wort does not undergo decay during the storage of the wort. The culture fluid for lysine is also obtained by fermenting the substrate on the basis of molasses in the presence of a suitable microorganism producing lysine for a period of 30 to 100 hours. The amount of lysine obtained in this case is usually in the range of 50-100 g / l. The processing of the concentrated wort with additives by the proposed method is carried out using different methods in the case of using lime in its raw form or in the form of hydrated lime. The method is carried out as follows. Quicklime is mixed in the mixer with a concentrated wort containing 60-85% by weight of dry matter, which usually corresponds to a lysine content of 10-40% by weight. With this treatment, the final product is obtained without further drying. In the preferred embodiment, a concentrated wort is used, the water content of which is brought to the lowest possible level and amounts to 15-40%, more specifically 15-30%.
    In one embodiment, the concentrated wort is mixed with quicklime, but in this case a drying of the obtained product is necessary in order to obtain the desired properties.
    The method can also be carried out as follows. Aqueous pulp consisting of concentrated wort and lime is sprayed in a fluidized bed. This produces granules that require additional drying. In this case, it is necessary to use a concentrated wort, the water content of which is sufficient for the pulp to pass well through the nozzle for spraying. An aqueous slurry consisting of concentrated wort and lime is also separated in a nozzle. In this case, the pulp must be diluted to a greater extent for ease of feeding. In both cases, the wort containing 30-70% (more specifically 30-50%) of water corresponds to good results.
    The amount of lime in terms of CaO, which gives satisfactory results, is in the range of 10-50%. Successfully use lime, consisting of particles of small size. Good results are obtained when using particles having a size less than 100 microns.
    Upon receipt of the final product with the desired properties by the proposed method, the mixture of lime and concentrated wort is exposed to carbon dioxide gas, either after or, preferably, during the mixing process. For example, mixing the concentrated wort with lime in a hermetic kneading mixer does not result in a satisfactory product; on the contrary, when carrying out the process in an atmosphere of carbon dioxide, a satisfactory product is obtained, and the residence time in this atmosphere can be from several minutes to one hour, depending on the amount the alkali used in this process, the water content of the wort concentrate, and the degree of recycling of the products. Carbon dioxide is the carbon dioxide gas that is contained in the air, but it can be supplied from an external source, in some cases under pressure. The use of carbon dioxide from an external source allows the process to be carried out at a faster rate, and also to use much smaller amounts of lime. Calcium carbonate, formed as a result of this process, allows to obtain the final product of the desired quality, while the natural calcium carbonate in the finished vvd, mixed with a concentrated wort, does not give any satisfactory results.
    The carbon dioxide content in the final product in the form of calcium carbonate is in the range of 2-30% (based on calcium carbonate).
    The lysine and lime based feeds obtained by the inventive method are solid compositions that are easy to handle and contain various components that are within the following limits, wt%:
    Lysine 10-35
    Other substances constituting the dry residue of the wort (except lysine) 20-60 Carbon dioxide (in terms of calcium carbonate in an effective form) 4-30 Total calcium content (in the form of slaked lime and calcium carbonate) 5-35. Water Else Significant interest is represented by compositions whose components are contained in the following ratios,%
    Lysine 20-35
    The dry residue of the wort (except lysine) is 40-50 CO2 (in terms of calcium carbonate) 8-20 Total calcium content 7-14 Water Else These components are characterized by good stability. After six months of storage at about a temperature, the lysine content of the final product does not change.
    The presence of calcium is consistent with animal feed requirements and is not uncomfortable.
    When precipitated magnesium carbonate or a mixture of lime and precipitated magnesium carbonate is used, B1I is a mixture of lime and / or precipitated magnesium carbonate with other mineral additives, for example, silica, silicates or aluminosilicates, the method is carried out in accordance with the description provided. .
    The total amount of the mineral additive introduced into the product usually lies in the range of 10-50 wt.% Of the weight of the final composite.
    The formulations provided are suitable for use as animal feed. These compositions, being hard and non-caking in the presence of moisture, mix well with various types of animal feed. Due to the stability of these compositions, there is no need to prepare the feed immediately before use.
    Example 1. A 1.6 liter Küstner mixer, equipped with two spiral blades for mixing and equipped with double walls for circulating cold water, is charged with 270 g of crushed quicklime. The rotation speed of the low-speed rotor is 30 rpm, and the rotation speed of the high-speed rotor is 60 rpm. 630 g of concentrated wort (70 wt.%) Are poured into the mixer. Five minutes after the start of mixing, a stream of carbon dioxide from the evaporation of dry ice is admitted to the mixer. The pasty mixture gradually solidifies and mixing is difficult. After about 30 minutes, the mixture is stratified to form chunks of varying degrees of readiness. In this way, 850 g of a light brown product is obtained, consisting of powder and small pieces more or less solid, the product is convenient to handle. The specified product contains 15 wt.% Lysine. After 8 hours in the atmosphere of saturated water vapor at 20 ° C, the product absorbs 6-7% moisture, but it retains the same structure and remains easy to handle.
    Example 2. A granulator torus dryer, operating using a fluidized bed, of the type STREA-1 of Societe Azromatic, loads 100 g of the product obtained according to Example 1, the lime content in which (as CaO) is close to 35%, crushed and millet up to a particle size of 500 microns.
    Air is blown into the granulator.
    in sufficient quantity to create and maintain a fluidized bed. The injected air contains carbon dioxide produced by the evaporation of dry ice.
    A slurry mixture is obtained consisting of 189 g of hydrated lime, preferably sieved to a particle size of 500 µm and 438 g of concentrated mash containing 63%
    water that is sprayed into the fluidized bed of the product at a flow rate of 2 l / h. The spray duration is 18 minutes. Upon expiration
    9min. The temperature of the air supporting the fluidized bed is then it is increased.
    to 48 ° C. After spraying is complete, the air is heated for up to
    10 min for complete drying of the product.
    So get 494 g of the product in the form of granules with a size less than 1 mm, having the following composition,%:
    Lysine Wort dry residue (except lysine) Lime (calcium oxide hydrate), Calcium carbonate Water
    After being left for 115 hours at about a temperature in an atmosphere corresponding to 100% moisture, the product absorbs 15% water without much change in physical properties. In particular, the product does not become sticky.
    Example 3. A fine grinding device type is used.
    LEA with a biconical chamber without a heat exchange shell with an annular nozzle with an inner diameter of 6 mm and an outer diameter of 8 mm, equipped with a nozzle on propane gas and a pump to introduce the mass to be dried. A slurry mix consisting of 2.24 kg of hydrated lime 8.32 kg of mash containing 3.30 kg of water and 0.6 kg of water for dilution is obtained. This mixture is introduced into the grinder by means of a pump. Basic operating parameters of the process: Air flow , 88 Temperature in the central part of the biconical chamber, ° C 170-142 Temperature at the inlet to the cyclone, from 1.48-128 Mixture feed rate, kg / h 35 Dry product is extracted at the base of the cyclone. The product is obtained in the form of a coffee powder with milk with a dense structure, dust-free 198 and good flow properties. It contains,%: Lysine20.2 Lime (based on CaSOH), 29.6 Calcium carbonate 2.7 Water2.5 Example 4. According to the method described in Example 1, 374 g of concentrated wort (containing 80% by weight solids, the amount of lysine in it is 22% by weight) to 160 g of Prolabo magnesium carbonate. After 2 minutes the mixing can be completed, resulting in 530 g of a light brown powder with good flow properties. Example 5. The same operations were carried out as in Example 4, replacing 50% by weight of magnesium carbonate with quicklime, and the result is a product in the form of a powder with good flow properties.
    权利要求:
    Claims (6)
    [1]
    1. METHOD FOR PRODUCING A FEEDING PRODUCT CONTAINING 15-20Z LYSINE, including mixing concentrated culture fluid obtained in the production of lysine with a mineral additive, characterized in that, in order to reduce hygroscopicity and improve stabilization of the feed, either lime is used as a mineral additive and mixing is carried out in the presence of carbon dioxide until the content of - is reached, lead in the finished product 29-35% and the content of calcium carbonate 2.5
    57 °, either precipitated magnesium carbonate until its content in the finished product reaches 30%, or a mixture of quicklime and magnesium carbonate until the content of finished lime 15% and magnesium carbonate 15% is reached.
    [2]
    2. The method according to claim 1, characterized in that the concentrated culture fluid obtained from the production of lysine with a content of 20-30% water is used.
    [3]
    3. The method according to claim 1, characterized in that the mixing of the concentrated culture fluid with mineral additives is carried out in a paddle mixer.
    [4]
    4. The method according to claim 1, characterized in that the mixture of culture fluid and additives is sprayed in the fluidized bed and dried.
    [5]
    5. The method of pop. 1, characterized in that the mixture of culture fluid and additives is sprayed in the atomizer.
    [6]
    6. The method of pop. 5, characterized in that they use a culture fluid with a water content of 40%.
    SU, t 1169519
    1 1169519
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    同族专利:
    公开号 | 公开日
    PL226418A1|1981-05-22|
    IT1141033B|1986-10-01|
    DK161557C|1992-01-27|
    DE3032618A1|1981-03-12|
    NL8004739A|1981-03-03|
    AU6177880A|1981-03-05|
    DK161557B|1991-07-22|
    FR2464032B1|1984-05-18|
    JPH0138459B2|1989-08-14|
    PL123994B1|1982-12-31|
    BE884970A|1981-03-02|
    CA1143605A|1983-03-29|
    ES494602A0|1981-04-01|
    JPS5635962A|1981-04-08|
    CH644995A5|1984-09-14|
    FR2464032A1|1981-03-06|
    DE3032618C2|1990-03-22|
    ES8103939A1|1981-04-01|
    NL190744C|1994-08-01|
    US4327118A|1982-04-27|
    IT8024377D0|1980-08-29|
    DK366980A|1981-03-01|
    NL190744B|1994-03-01|
    GB2057244A|1981-04-01|
    GB2057244B|1983-05-18|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    DE139205C|
    US2665209A|1951-07-31|1954-01-05|Commercial Solvents Corp|Noncaking feed supplement|
    JPS4732556U|1971-04-28|1972-12-12|
    FR2135805A5|1971-04-29|1972-12-22|Ho Ching Tang|Glutamic acid and animal fodder prodn - from carbohydrate -contg materials by fermentation|
    SU480397A1|1972-06-30|1975-08-15|Институт Микробиологии Им.А.Кирхенштейна|The method of obtaining feed concentrate lysine|
    CS163505B1|1972-11-15|1975-09-15|
    SU494040A1|1973-04-12|1978-04-15|Институт Микробиологии Им.Августа Кирхенштейна Ан Латвийской Сср|Method of preparing l-lysine|
    SU488578A1|1974-03-27|1975-10-25|Всесоюзный Научно-Исследовательский Институт Маслодельной И Сыродельной Промышленности|The method of obtaining dry protein fortifier from whey|
    US4027043B1|1975-10-28|1986-04-08|
    US4016296A|1976-03-18|1977-04-05|Milo Don Appleman|Animal feed block|
    US4160041A|1977-02-14|1979-07-03|Jack J. Schroeder|Method of preparing a solid animal feed supplement|
    US4232045A|1977-10-06|1980-11-04|Standard Brands Incorporated|Preparation of free-flowing particulate yeast|
    JP4732556B2|1999-01-29|2011-07-27|戸田工業株式会社|Nonmagnetic particle powder for nonmagnetic underlayer of magnetic recording medium, method for producing the same, and magnetic recording medium|BG49602A3|1981-10-30|1991-12-16|Lilly Co Eli|Method for manifacture of foods for animals|
    DE3242501C1|1982-11-18|1984-03-29|Degussa Ag, 6000 Frankfurt|Use of aqueous L-lysine solutions to supplement feed with L-lysine|
    JPH0369493B2|1983-03-02|1991-11-01|Ajinomoto Kk|
    FR2541867B1|1983-03-03|1987-06-05|Aec Chim Organ Biolog|NOVEL COMPOSITIONS FOR LYSINE-BASED ANIMAL FEEDING AND THEIR PREPARATION|
    US5122512A|1988-09-12|1992-06-16|Pitman-Moore, Inc.|Swine growth promoting composition|
    ZA951426B|1994-02-28|1995-12-07|Aeci Ltd|Lysine products|
    AU706285B2|1995-05-16|1999-06-10|Ajinomoto Co., Inc.|Feed additive|
    CA2255130A1|1997-12-16|1999-06-16|Archer Daniels Midland Company|Process for making granular l-lysine feed supplement|
    US5990350A|1997-12-16|1999-11-23|Archer Midland Company|Process for making granular L-lysine|
    CN1236690C|1999-06-23|2006-01-18|德古萨股份公司|Water-containing animal feed additive with lysine and its producing method|
    DK2262894T3|2008-03-03|2014-09-29|Global Bio Chem Technology Group Company Ltd|Recombinant microorganisms and method for preparing L-lysine|
    MX342935B|2009-12-21|2016-10-19|Archer Daniels Midland Co|Processes for modifying protein digestion of ruminant feeds and products produced therefrom.|
    US20130136827A1|2011-11-28|2013-05-30|James S. Drouillard|Method and Composition for Increasing The Proportion of Dietary Ingredients That Are Resistant To Degradation by Ruminal Microorganisms|
    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    FR7921646A|FR2464032B1|1979-08-29|1979-08-29|
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